Methyl 2-diazo-3-oxobutanoate - Names and Identifiers
Methyl 2-diazo-3-oxobutanoate - Physico-chemical Properties
| Molecular Formula | C5H6N2O3
|
| Molar Mass | 142.11274 |
Methyl 2-diazo-3-oxobutanoate - Upstream Downstream Industry
Methyl 2-diazo-3-oxobutanoate - Introduction
Methyl 2-diazo-3-oxobutanoate (Methyl 2-diazo-3-oxobutanoate) is an organic compound with the formula C5H6N2O3. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
1. Appearance: colorless to yellow crystal or liquid.
2. Melting point: about 26-30 ° C.
3. Boiling Point: about 120-130 ° C.
4. Solubility: Soluble in some organic solvents, such as ethanol and ether.
Use:
Methyl 2-diazo-3-oxobutanoate is mainly used for diazo reaction and cyclization reaction in organic synthesis. It is commonly used as a diazo nucleophile or coupling reagent. In addition, the compounds are useful in the synthesis of natural products such as alkaloids and pharmaceutical intermediates.
Method:
Methyl 2-diazo-3-oxobutanoate can be obtained by different synthetic routes. One common method is by the reaction of methyl hydroxy 2-ketobutyrate with sodium diazotization. The specific preparation method involves the technology of organic synthesis, and the reaction conditions need to be strictly controlled.
Safety Information:
1. Methyl 2-diazo-3-oxobutanoate is a potentially dangerous compound, which belongs to combustibles and is easy to release toxic gases.
2. In the process of operation, need to take appropriate protective measures, including wearing chemical protective clothing, gloves and goggles.
3. This compound may be irritating and corrosive to the skin, eyes and respiratory system, so direct contact and inhalation should be avoided.
4. When storing and handling, keep it in a closed container, away from heat and fire.
5. When using the compound, follow the laboratory safety operating procedures and ensure that the operation is carried out under the supervision of professionally trained personnel.
Last Update：2024-04-09 20:49:11